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1

THE EFFECT OF FOOD ON CABERGOLINE PHARMACOKINETICS AND TOLERABILITY IN HEALTHY VOLUNTEERS

S. Persiani, M. Rocchetti, M. A. Pacciarini, Beverly Holt, Steve Toon, Margherita Strolin-Benedetti

Journal:

Biopharmaceutics & Drug Disposition

Year:

1996

Language:

english

File:

PDF, 734 KB

english, 1996

2

Preliminary pharmacokinetic study of ibuprofen enantiomers after administration of a new oral formulation (ibuprofen arginine) to healthy male volunteers

Gianfranco Fornasini, Nunzia Monti, Giandomenico Brogin, Maddalena Gallina, Mario Eandi, Stefano Persiani, Massimo Bani, Carlo Della Pepa, Gianpaolo Zara, Margherita Strolin Benedetti

Journal:

Year:

1997

Language:

english

File:

PDF, 155 KB

english, 1997

3

Is it important to correct apparent drug tissue concentrations for blood contamination in the dog?

Christine Giudicelli, Eric Dricot, Frédérique Moati, Margherita Strolin-Benedetti, Jean-François Giudicelli

Journal:

Fundamental & Clinical Pharmacology

Year:

2004

Language:

english

File:

PDF, 162 KB

english, 2004

4

(R) salsolinol N-methyltransferase activity increases in parkinsonian lymphocytes

Dr Makoto Naoi, Wakako Maruyama, Naoki Nakao, Tohru Ibi, Ko Sahashi, Margherita Strolin Benedetti

Journal:

Annals of Neurology

Year:

1998

Language:

english

File:

PDF, 427 KB

english, 1998

5

Stereoselective and species-dependent kinetics of reboxetine in mouse and rat

Margherita Strolin Benedetti, Enrico Frigerio, Paola Tocchetti, Giannantonio Brianceschi, Maria Grazia Castelli, Cinzia Pellizzoni, Dr. Philippe Dostert

Journal:

Year:

1995

Language:

english

File:

PDF, 372 KB

english, 1995

6

Improved bioavailability of a new oral preparation of medroxyprogesterone acetate

Marie-Christine Etienne, Gerard Milano, Nicole Rene, Margherita Strolin Benedetti, Constantin Efthymiopoulos, Marie-Louise Vo Van Patrick Hurteloup, Philippe Montcuquet, Marc Frenay, Moïse Namer

Journal:

Journal of Pharmaceutical Sciences

Year:

1991

Language:

english

File:

PDF, 397 KB

english, 1991

7

Interactions of monoamine oxidase with substrates and inhibitors

Philippe L. Dostert, Margherita Strolin Benedetti, Keith F. Tipton

Journal:

Medicinal Research Reviews

Year:

1989

Language:

english

File:

PDF, 2.69 MB

english, 1989

8

Biotransformation of xenobiotics by amine oxidases

Margherita Strolin Benedetti

Journal:

Fundamental & Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 265 KB

english, 2001

9

Absorption and disposition of levocetirizine, the eutomer of cetirizine, administered alone or as cetirizine to healthy volunteers

Eugène Baltes, René Coupez, Hilde Giezek, Gudrun Voss, Carsten Meyerhoff, Margherita Strolin Benedetti

Journal:

Fundamental & Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 159 KB

english, 2001

10

Blood distribution of levocetirizine, a new non-sedating histamine H1-receptor antagonist, in humans

Françoise Bree, Laetitia Thiault, Gwenaelle Gautiers, Margherita Strolin Benedetti, Eugène Baltes, Jean-Pierre Rihoux, Jean-Paul Tillement

Journal:

Fundamental & Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 155 KB

english, 2002

11

Idarubicin metabolism and pharmacokinetics after intravenous and oral administration in cancer patients: a crossover study

Carlo M. Camaggi, Elena Strocchi, Patrizia Carisi, Andrea Martoni, Alessandra Tononi, Monica Guaraldi, Margherita Strolin-Benedetti, Constantin Efthymiopoulos, Franco Pannuti

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.05 MB

english, 1992

12

Clinical pharmacology of the new COMT inhibitor CGP 28 014

Peter R. Bieck, Karl-Heinz Antonin, Gisbert Farger, Erik B. Nilsson, Eckhart K. Schmidt, Philippe Dostert, Margherita Strolin Benedetti, Peter C. Waldmeier

Journal:

Neurochemical Research

Year:

1993

Language:

english

File:

PDF, 403 KB

english, 1993

13

Pharmacokinetics and metabolism of14C-levetiracetam, a new antiepileptic agent, in healthy volunteers

Margherita Strolin Benedetti, Rhys Whomsley, Jean-Marie Nicolas, Colin Young, Eugène Baltes

Journal:

European Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 306 KB

english, 2003

14

Inhibition of allergen-induced wheal and flare reactions by levocetirizine and desloratadine

Nelly Frossard, Margherita Strolin-Benedetti, Ashok Purohit, Gabrielle Pauli

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 734 KB

english, 2008

15

Age-Related Changes in Aldehyde Dehydrogenase Activity of Rat Brain, Liver, and Heart

Hung Cao Danh, Margherita Strolin Benedetti, Philippe Dostert

Journal:

Journal of Neurochemistry

Year:

1983

Language:

english

File:

PDF, 588 KB

english, 1983

16

Differential Changes in Superoxide Dismutase Activity in Brain and Liver of Old Rats and Mice

Hung Cao Danh, Margherita Strolin Benedetti, Philippe Dostert

Journal:

Journal of Neurochemistry

Year:

1983

Language:

english

File:

PDF, 508 KB

english, 1983

17

The Metabolism of Dopamine by Both Forms of Monoamine Oxidase in the Rat Brain and Its Inhibition by Cimoxatone

Christopher J. Fowler, Margherita Strolin Benedetti

Journal:

Journal of Neurochemistry

Year:

1983

Language:

english

File:

PDF, 716 KB

english, 1983

18

Cimoxatone Is a Reversible Tight-Binding Inhibitor of the A Form of Rat Brain Monoamine Oxidase

Christopher J. Fowler, Margherita Strolin Benedetti

Journal:

Journal of Neurochemistry

Year:

1983

Language:

english

File:

PDF, 342 KB

english, 1983

19

Enzyme induction and inhibition by new antiepileptic drugs: a review of human studies

Margherita Strolin Benedetti

Journal:

Fundamental & Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 1.79 MB

english, 2000

20

Amine oxidases and monooxygenases in the in vivo metabolism of xenobiotic amines in humans: has the involvement of amine oxidases been neglected?

Margherita Strolin Benedetti, Keith F. Tipton, Rhys Whomsley

Journal:

Fundamental & Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 177 KB

english, 2007

21

Authors’ reply

Margherita Strolin Benedetti, Christian Otoul

Journal:

Fundamental & Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 43 KB

english, 2009

22

The deamination of noradrenaline and 5-hydroxytryptamine by rat brain and heart monoamine oxidase and their inhibition by cimoxatone, toloxatone and MD 770222

Margherita Strolin Benedetti, Thierry Boucher, Christopher J. Fowler

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1983

Language:

english

File:

PDF, 637 KB

english, 1983

23

Pharmacokinetics and pharmacodynamics of the antiarrhythmic compound MD750819 in dogs with experimentally induced arrhythmias

James Dow, Bernard Laquais, Jacky Tisne-Versailles, Bernard Pourrias, Margherita Strolin Benedetti

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1982

Language:

english

File:

PDF, 848 KB

english, 1982

24

Estimation of the elimination half-life of the monoamine oxidase inhibitor cimoxatone in rat brain on the basis of ex vivo inhibition data

Christopher J. Fowler, Margherita Strolin Benedetti, Vincenzo Rovei

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

1983

Language:

english

File:

PDF, 512 KB

english, 1983

25

Absorption, distribution, metabolism and excretion of [14C]levocetirizine, theRenantiomer of cetirizine, in healthy volunteers

Strolin Benedetti, Margherita, Plisnier, Michel, Kaise, Jacques, Maier, Laura, Baltes, Eug&#x000E8, ne, Arendt, Catherine, McCracken, Nigel

Journal:

European Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 175 KB

english, 2001

26

Drug metabolism in the paediatric population and in the elderly

Margherita Strolin Benedetti, Rhys Whomsley, Michael Canning

Journal:

Drug Discovery Today

Year:

2007

Language:

english

File:

PDF, 289 KB

english, 2007

27

Continuous versus on-demand pharmacotherapy of allergic rhinitis: Evidence and practice

Gert Laekeman, Steven Simoens, Johan Buffels, Michel Gillard, Thibert Robillard, Margherita Strolin Benedetti, Jean-Baptiste Watelet, Georges Liekendael, Liesbet Ghys, Martin Church

Journal:

Respiratory Medicine CME

Year:

2011

Language:

english

File:

PDF, 434 KB

english, 2011

28

Involvement of enzymes other than CYPs in the oxidative metabolism of xenobiotics

Strolin Benedetti, Margherita, Whomsley, Rhys, Baltes, Eugène

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2006

Language:

english

File:

PDF, 364 KB

english, 2006

29

Interaction of diftalone and some of its metabolites with human serum proteins

Alessandro Assandri, Aurelio Zerial, Margherita Strolin-Benedetti, Antonio Perazzi

Journal:

Biochemical Pharmacology

Year:

1975

Language:

english

File:

PDF, 281 KB

english, 1975

30

Inhibition by aminoacetonitrile and propargylamine of glycine cleavage system from rat brain and liver mitochondria

Jesus Benavides, Nicole Croci, Margherita Strolin Benedetti

Journal:

Biochemical Pharmacology

Year:

1983

Language:

english

File:

PDF, 321 KB

english, 1983

31

Intestinal metabolism of tyramine by both forms of monoamine oxidase in the rat

Margherita Strolin Benedetti, Thierry Boucher, Arvid Carlsson, Christopher J. Fowler

Journal:

Biochemical Pharmacology

Year:

1983

Language:

english

File:

PDF, 459 KB

english, 1983

32

Evidence that (+)[3H]amphetamine binds to acceptor sites which are not MAO-A

Ariane Lesage, Margherita Strolin, Benedetti, Jean Francois Rumigny

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 361 KB

english, 1985

33

Inhibition of cytochrome P-450-dependent oxidation reactions by mao inhibitors in rat liver microsomes

Hervé Dupont, Donald S. Davies, Margherita Strolin-Benedetti

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 697 KB

english, 1987

34

Monoamine oxidase, brain ageing and degenerative diseases

Margherita Strolin Benedetti, Philippe Dostert

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 923 KB

english, 1989

35

Is the oxidation of milacemide by monoamine oxidase a major factor in its anticonvulsant actions?

Eimear M. O'Brien, Keith F. Tipton, Margherita Strolin Benedetti, Alberto Bonsignori, Pietro Marrari, Philippe Dostert

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 673 KB

english, 1991

36

The dispositional enantioselectivity of indobufen in man

Margherita Strolin Benedetti, Enrico Frigerio, Vittore Tamassia, Giorgio Noseda, John Caldwell

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 286 KB

english, 1992

37

In vivo interaction of cabergoline with rat brain dopamine receptors labelled with [3H]N-n-propylnorapomorphine

Margherita Strolin Benedetti, Philippe Dostert, Domenico Barone, Constantin Efthymiopoulos, Giovanni Peretti, Romeo Roncucci

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 754 KB

english, 1990

38

Continuous versus on-demand pharmacotherapy of allergic rhinitis: Evidence and practice

Gert Laekeman, Steven Simoens, Johan Buffels, Michel Gillard, Thibert Robillard, Margherita Strolin Benedetti, Jean-Baptiste Watelet, Georges Liekendael, Liesbet Ghys, Martin Church

Journal:

Respiratory Medicine

Year:

2010

Language:

english

File:

PDF, 374 KB

english, 2010

39

A neurotoxin N-methyl(R)salsolinol induces apoptotic cell death in differentiated human dopaminergic neuroblastoma SH-SY5Y cells

Wakako Maruyama, Margherita Strolin Benedetti, Tsutomu Takahashi, Makoto Naoi

Journal:

Neuroscience Letters

Year:

1997

Language:

english

File:

PDF, 88 KB

english, 1997

40

Pharmacokinetics in special populations

Poggesi, Italo, Benedetti, Margherita Strolin, Whomsley, Rhys, Lamer, Sophie Le, Molimard, Mathieu, Watelet, Jean-Baptiste

Journal:

Drug Metabolism Reviews

Year:

2009

Language:

english

File:

PDF, 1.32 MB

english, 2009

41

Absorption, disposition and preliminary metabolic pathway of 14 C-rifabutin in animals and man

Battaglia, Rosangela, Pianezzola, Elio, Salgarollo, Giuliana, Zini, Guido, Benedetti, Margherita Strolin

Journal:

Journal of Antimicrobial Chemotherapy

Year:

1990

Language:

english

File:

PDF, 451 KB

english, 1990

42

Relevance of H1-receptor occupancy to H1-antihistamine dosing in children

Simons, Keith J., Benedetti, Margherita Strolin, Simons, F. Estelle R., Gillard, Michel, Baltes, Eugene

Journal:

Journal of Allergy and Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 399 KB

english, 2007

43

Drug metabolism and pharmacokinetics

Benedetti, Margherita Strolin, Whomsley, Rhys, Poggesi, Italo, Cawello, Willi, Mathy, François-Xavier, Delporte, Marie-Laure, Papeleu, Peggy, Watelet, Jean-Baptiste

Journal:

Drug Metabolism Reviews

Year:

2009

Language:

english

File:

PDF, 2.48 MB

english, 2009

44

Supplement 9: Toxicological Evaluation of Chemical Interactions || Induction and Autoinduction Properties of Rifamycin Derivatives: A Review of Animal and Human Studies

Margherita Strolin Benedetti and Philippe Dostert

Journal:

Environmental Health Perspectives

Year:

1994

Language:

english

File:

PDF, 1.09 MB

english, 1994

45

Therapeutic management of allergic diseases

Watelet, Jean-Baptiste, Gillard, Michel, Benedetti, Margherita Strolin, Lelièvre, Bénédicte, Diquet, Bertrand

Journal:

Drug Metabolism Reviews

Year:

2009

Language:

english

File:

PDF, 3.61 MB

english, 2009

46

Aim of this special issue

Church, Martin K., Benedetti, Margherita Strolin, Watelet, Jean-Baptiste

Journal:

Drug Metabolism Reviews

Year:

2009

Language:

english

File:

PDF, 498 KB

english, 2009

47

A small molecule that mimics the metabolic activity of copper-containing amine oxidases (CuAOs) toward physiological mono- and polyamines

Largeron, Martine, Fleury, Maurice-Bernard, Strolin Benedetti, Margherita

Journal:

Organic & Biomolecular Chemistry

Year:

2010

Language:

english

File:

PDF, 195 KB

english, 2010

48

Drug interactions

Boobis, Alan, Watelet, Jean-Baptiste, Whomsley, Rhys, Benedetti, Margherita Strolin, Demoly, Pascal, Tipton, Keith

Journal:

Drug Metabolism Reviews

Year:

2009

Language:

english

File:

PDF, 1.78 MB

english, 2009

49

General conclusions

Watelet, Jean-Baptiste, Benedetti, Margherita Strolin, Church, Martin K, Oesch, Franz

Journal:

Drug Metabolism Reviews

Year:

2009

Language:

english

File:

PDF, 509 KB

english, 2009

50

From pharmacokinetics to therapeutics

Church, Martin K., Gillard, Michel, Sargentini-Maier, Maria Laura, Poggesi, Italo, Campbell, Alison, Benedetti, Margherita Strolin

Journal:

Drug Metabolism Reviews

Year:

2009

Language:

english

File:

PDF, 1.62 MB

english, 2009